for the significance to priority areas, you simply think about each of the areas of the Ottawa Charter, and choose the one that is most significant in combatting it...
for example, for CVD, developing personal skills is most significant because CVD is predominantly caused by modifiable lifestyle factors.
For how the 5 areas interact, i think you basically just say how they are closely linked to one another... like e.g. creating supportive environments and strengthening community action can interact for example if the community establishes a program that creates an environment that supports people with a condition, there is a strong link between the two... u just say how there is a strong link between all the ottawa charter areas...
hope that made sense!!