Hands down my most favourite anime would be Jojo's bizzare adventure. It's surprisingly unique and fresh for a shounen manga despite being old. (Started in 1987).
Besides Jojo; I also really like:
Hunter X Hunter
Full Metal Alchemist Brotherhood
Code Geass
Parastye
Future Diary
Attack on titan
Steins;Gate
Re:zero
I don't really get to watch niche/seasonal anime (I didn't really have much time cause HSC and other factors) so most my favourites are more well known/popular.
In terms of manga, it's kinda hard to decide between The World God Only Knows or My hero academia. Death note, Magi, Tokyo Ghoul and Seven deadly sins are pretty high up my list as well. Death note after a certain event kinda felt dragged on. Magi's current arc is pretty boring. Tokyo Ghoul :re had so many character introduced and killed its kinda hard to keep up. Also the fight scenes are drawn so weirdly its hard to tell what's going on (Though I mainly read it for the plot and seeing kaneki suffer). There isn't anything bad so far in Seven deadly sins and is a solid manga series.