I don't see the comparison that everybody seems to think: The X-Files meets Lost. Sure, its a sci-fi and the first scene involved an airplane with 108 (4+8+15+16+23+42) passengers and Lance Reddick appears in both shows but other then that, it draws no comparisons with Lost.
The pilot was okay, but the plot twist at the end had me thinking, we followed the main protagonists attempts to heal her lover from imminent death (I wouldn't go as far and say that he was her boyfriend) only for him to die in the end and turns out he was working for the opposing side? The whole episode kind of seemed pointless then once you thought about it that way other than to provide a means to introduce the main characters (which I guess, is the purpose of a pilot). But, I'm sure things will pick up throughout the season.